On baseline grids
Jason Santa Maria about the reasons why baseline grids are not native to the web and should be avoided:
It’s incredibly difficult to maintain a baseline grid in a medium as inconsistent and fluid as a web page. Images, form elements, rendering differences between browsers and platforms: these can all throw a baseline grid out of phase. This only gets worse when you’re setting up a design for someone else to implement or maintain, as we often do in client work. In other words, if you’re not intimately familiar with the intricacies of a given grid system, it’s incredibly easy to mess it up.